Micro Silica Derma
Clinical Results
Micro Silica Derma has clinically proven results. Below is data from two independent studies that have been published in peer-reviewed journals.
PCR Studies
There is good evidence that certain silicon-containing materials promote wound healing and their common feature is the delivery of OrthoSilicic acid (Si(OH)4) either directly or following metabolism.
Silica was shown to be non-toxic for all forms and concentrations tested and whilst the anticipated stimulatory effect of OrthoSilicic acid was observed, the silica NPs also stimulated fibroblast proliferation and migration. In particular, the amine functionalized particles promoted wound closure more rapidly than soluble OrthoSilicic acid alone. We suggest that this effect is related to easy cellular internalization of these particles followed by their intra-cellular dissolution releasing silicic acid at a faster rate than its direct uptake from the medium.
Our findings indicate that amorphous silica-based NPs may favour the delivery and release of bioactive silicic acid to cells, promoting wound healing.
Source: https://www.sciencedirect.com/science/article/pii/S0927776517302357?via%3Dihub
Instant Moisturization
[PCR study Corneometer measurement]
Improvement of Skin Barrier
[PCR study TEWL measurement]
Hydration Levels
[PCR study Nova Meter measurement]
Science behind μ-Silica Derma™
μ-Silica Derma™ contains absolutely no oil or grease. The ointment is 100% water-soluble and spreads easily and evenly over the skin – even if moisture is present. Unlike all other treatments, it can be gently and easily removed with just water.
μ-Silica Derma™ has humectant ingredients that increase the skin’s ability to retain moisture. They leave a pleasant feel on the skin, similar to the natural replacement of oils, but without a greasy or sticky sensation.
Moreover, they comply with stringent regulatory requirements for pharmaceutical and personal care products.
μ-Silica Derma™ contains a specially formulated silicon compound that optimizes the delivery of OrthoSilicic Acid (OSA), a naturally occurring molecule that is associated with healthy connective tissue growth.
*Research shows that OSA accelerates wound cicatrisation by stimulating basal epidermal and dermal fibroblast cells to upregulate expression of basic fibroblast growth factor (β-FGF). Moreover, collagen and elastin fibers formed in the presence of OSA are more densely packed, better organized and more homogenously distributed (possibly due to activation of hydroxylation enzymes). [Reffitt, D.M. et al. Bone 2003, 32, 127-35; Hanasano, M. et al. Arch. Facial Plast. Surg. 2004, 6, 88-93; Herreros, F.O. et al. Arch. Dermatol. Res. 2007, 299, 41-45.]
Erythema (Redness)*
Edema (Swelling)*
[PCR study PI assessment]